NEET : Multiple Choice questions: Protein Synthesis or Translation

1. Consider the following statement and select the correct the number of correct statements.
1. The polymerisation of amino acids in form of polypeptide chain according to sequence codon is translation.
2. Translation occurs at ribosome in cytoplasm of cell.
3.Translation uses mRNA that is formed through transcription.

4. Anticodon on tRNA do not play any role in translation.

5. Codon which determines the sequences of amino acids, present on rRNA.

A. Four         B. Three

C. Five         D. Two

Answer:  B Explanation 

2. As hnRNA is transcribed into mRNA after splicing, mRNA is attached with 

A. Smaller subunit of ribosome

B. Larger subunit of Ribosome

C. Rough endoplasmic reticulum 

D. Smooth endoplasmic reticulum

Answer:  A Explanation 

3. Which one of the following is first step of Protein synthesis.

A. Charging of tRNA

B. Aminoacylation of tRNA

C. Attachment of mRNA with ribosome

D. Formation of peptide bond between amino acids

Answer:  C Explanation 

4. Which one of the following is initiation codon for Protein synthesis.

A. GAG             B. GUG

C. AUG             D. UGA

Answer:  C Explanation

5. Which one of the following statement is not correct for Protein synthesis.

A. mRNA is attached with smaller subunit of Ribosome in such a way that initiation codon is read as earlier.

B. tRNA molecule is charged with help of aminoacyl synthese enzyme and ATP.

C. Charged tRNA enters at smaller subunit of Ribosome.

D. Charged tRNA means that amino acid is attached with its accepter end.

Answer:  C Explanation

6. Consider the following statement and select the correct code:

1. Charged tRNA enters through A site of larger subunit of ribosome.

2. tRNA molecule accept amino acids according to anticodon present on its another end.

3. tRNA molecule leave amino acid at larger sub unit of Ribosome according to codon present on mRNA.

A. 1 and 2       B. 2 and 3

C. 1 and 3      D. 1, 2 and 3

Answer:  D Explanation

 

7. Once one amino acid is left at larger subunit of Ribosome than which one of the following is flanked to link another amino acid.

A. mRNA           

B. tRNA

C. Ribosome     

D. mRNA and Ribosome

Answer:  D Explanation

8. Which one of the following  is not associated with larger subunit of Ribosome.

A. Attachment of mRNA 

B. Leaving of amino acid by tRNA

C. Entry of charged tRNA with amino acid 

D. Linking of amino acids through peptide bond 

Answer:  A  Explanation

9. Which one of the following statement is not correct for Protein synthesis.

A. As Ribosome move from codon to codon, amino acids are added one by one  with the help of tRNA.

B. As anticodon of tRNA is matched with codon of mRNA than amino acids are attached in form of polypeptide chain.

C. As amino acids are left at larger subunit by tRNA than peptide bond is formed between the amino acids.

D. As Polypeptide chain is formed that it releases from ribosome and stored at smaller subunit of Ribosome.

Answer:  D  Explanation

10. A polypeptide chain is formed at larger subunit of Ribosome due to presence of enzyme 

A. Peptidyle transferase

B. Protease 

C. Phoshodiesterase 

D. Peptidyle dehydrogenase

 Answer:  D  Explanation

11. Which one of the following is/are termination codon or stop codon.

A. UAA  

B. UGA 

C. UAG 

D. All of the above 

Answer:  D  Explanation

12. Consider the following statement about the termination codon and select the correct code:

1. They are involved in termination of synthesis of polypeptide chain.

2. They do not code for any amino acids

3. There are no tRNA for termination codon.

A. 1 and 2       B. 2 and 3

C. 1 and 3      D. 1, 2 and 3

Answer:  D Explanation

13. Which of the following statement is not correct for the  Untranslated region (UTR).

A. These are additional sequences on mRNA which are not translated during protein synthesis .

B. These are specific  sequences on tRNA which are not translated during protein synthesis .

C. UTR can be present on both 3' end and 5' end.

D. UTR are present before Initiation codon and after termination codon.

Answer:  B Explanation

14. Which of the following factor help to release newly synthesized protein chain from ribosome to cytoplasm.

A. Sigma factor

B. Rho factor

C. Omega factor

D. Release factor

Answer:  D Explanation

15. Identify the A, B, C D in the diagram.

     A           B          C        D

A. mRNA  tRNA      3'       5'

B. mRNA  tRNA      5'       3'

C. tRNA    mRNA    3'       5'

D. tRNA    mRNA    5'       3' 

Answer: D