NEET : Multiple Choice questions:Frederick Griffith transformation Experiment

1. In which of the following year, Griffith conducted transformation experiment.

A. 1928          B. 1930

C. 1925          D. 1940

Answer: A Explanation 

2. Griffith used  which of the following bacteria for his   transformation experiment.

A. Haemophilia influenzae

B. Streptococcus pneumonae

C. Proteus vulgaris          

D. Salmonella typhi

Answer: B Explanation 

3.Which of the following statement is not correct about streptococcus pneumonae used by  Griffith for  transformation experiment.

A. Smooth colony bacteria is responsible to spread pneumonia infection.

B. Rough strain bacteria do not have polysaccharide coat hence it is not virulent.        

 C. Smooth strain bacteria has polysaccharide coat hence it is virulent.

D..Griffith took mouse in his experiment along with two strain of bacteria.

Answer: D Explanation 

4. Which of the following is not fit in series of experiment conducted by Griffith.

A. Mice infected with smooth strain : died due to pneumonia 

B. Mice infected with rough strain : Mice alived 

C. Mice infected with heat killed smooth strain : Mice alived

D. Mice infected with mixture of rough strain and heat killed Smooth strain :Mice  alived.

Answer: D Explanation

5.Which of the following statement is not correct about  Griffith 's

transforation experiment.

A. Griffith conducted his experiment to discover the factor as unit of inheritance described by Mendal 

B.With the infection of heat killed smooth strain, Mice alived because polysaccharide coat was destroyed on heating.

C. Streptococcus pneumonae has two strain : S Strain and R strain.

D. Mice died with the infection of smooth strain due to presence of polysaccharide coat.

Answer: A Explanation 

6.Consider the statement about the  conclusion  made by   Griffith 's at end of 

experiment and select the correct code.

1.Somehow S strain bacteria had been transformed by R strain bacteria.

2. The R strain inherited some transforming principle’ from the heat-killed S strain bacteria which made them virulent.

3. Somehow R strain bacteria had been transformed by S strain bacteria.

4. The heat killed S strain inherited some transforming principle’ from the R strain bacteria which made them virulent.

A. 1 and 2 B. 2 and 3

C. 1 and 3 D. 2 and 4

Answer: B Explanation

7. Who of the following was not associated reworked the Griffith experiment to explore the  biochemical nature of the hereditary material.

A. Maurice Wilkins

B.Oswald Avery

C.Colin Macleod

D. Maclyn McCarty

Answer: A Explanation

8. Which of the following statement is incorrect about the biochemical experiment conducted by Avery, Macleod and McCarty.

A. They extracted  proteins, DNA, RNA and other biomolecules from the heat-killed S strain bacteria.

B. They observed that Protease and RNase enzyme did not affect the transformation from S- Strain

to R- Strain.

C. They ultimately proved that DNA is genetic material and all the Biologist were convinced.

D. They stated that DNase changed the result of transformation.

Answer : C Explanation

9. According to Avery, Macleod and McCarty, Which of the following enzyme changed the result of transformation.

A. Protease 

B. DNase

C. RNase

D. None of the above 

Answer: B Explanation

10. Which of the following year is associated with the work of Avery, Macleod and McCarty.

A. 1955 to 1966

B. 1944 to 1955

C. 1933 to 1944

D. 1966 to 1977

Answer: C Explanation