NEET : Multiple Choice questions: Packaging of DNA helix

1 . Which of the following statement is not correct about the packaging of DNA in E.coli.

A. DNA is not scattered through out the cell.

B. In Prokaryotes, DNA is packed in form of Nucleosome .

C. DNA is organised in form of large loop as nucleoid.

D. Negative charged DNA is held by the postive charged protein.

Answer: B Explanation 

2 . In Eukaryotic, DNA is packed in form of 

A. Nucleosome 

B. Nucleoid

C. Nucleolus

D. Nucellus

Answer: A Explanation

3. In Eukaryotic, Nucleosome is made up of 

A. Postively charged Histone octamer and Postively charged DNA

B. Postively charged Histone octamer and Negatively charged DNA

C. Negatively charged Histone octamer and Negatively charged DNA

D. Negatively charged Histone octamer and Postively charged DNA

Answer: B Explanation

4. Which of the following statement is not correct.

A.  A nucleosome is part of DNA that is wrapped around a core of proteins

B. Under Electron microscopic, Nucleosome appear like beads on string.

C. The packaging of Chromatin require high level of additional protein called Non histone protein.

D. A nucleosome is the basic structural unit of DNA packaging in Prokaryotes.

Answer: D Explanation

5. Histone protein is basic in nature due to presence of which of the following two amino acids

A. Arginine and Leucine

B. Arginine and Lysine

C. Tyrosine and Lysine

D. Methionine and Arginine

Answer: B Explanation

6.Which of the following statement is/ are  correct for histone protein .

A. It is positively charged and basic in nature .

B. It comprises eight protein hence called octamer.

C. It has two basic amino acids : Arginine and Lysine

D. All of the above

Answer: D Explanation

7. A nucleosome is connected to another Nucleosome by a linker protein called as 

A. H2B          B. H3B

C. H 1            D. H3

Answer: C  Explanation

8. Which of the following set of protein is part of Histone octamer.

A. H2A, H2B, H3, and H4

B. H1, H2B, H3, and H4

C. H2A, H1, H3, and H4

D. H2A, H2B, H1, and H4

Answer: A Explanation

9. Study the given Diagram and select the correct option

     A             B            C

A. DNA        H2        Histone

B. DNA        H1        Histone

C. Histone  DNA       H1

D. Histone    H1         DNA

Answer: B Explanation

10. The number of base pairs in each nucleosome 

A. 200            B. 400

C. 100            D. 300

Answer: A Explanation

11. Which of the following statement is not correct for Heterochromatin.

A.These chromatin are densely packed.

B. These give dark stain on staining. 

C. These are transcriptionally active.

D.These chromatin are insert or inactive.

Answer: C  Explanation

12. Which of the following statement is/are  correct for Euchromatin.

A.These chromatin are loosely packed.

B. These give light stain on staining. 

C. These are transcriptionally active.

D. All of the above 

Answer: D  Explanation