NEET: Multiple Choice questions: Meselson and Stahl Experiment


1. Who of the following proved that DNA replication is semiconservative in nature. 

A. Fredrick Griffith 
B. Wilkins and Franklin 
C. Hershey and Chase 
D.Meselson and stahl
Answer: D Explanation 

2. DNA replication is semiconservative in nature it means that During replication 
A. DNA Helix is half opened.
B. One strand of DNA is synthesized into fragment.
C. One strand of DNA is old and another strand is newly synthesised.
D. None of the above
Answer: C Explanation 

3. Which of the following statement is not correct about the experiment of Meselson and stahl.
A. They grew or cultured E.coli in synthetic medium.
B. This medium contained ammonium chloride.
C. Synthetic ammonium chloride has 14N as it's constituent.
D. They used heavy isotope of nitrogen in synthetic medium.
Answer: C Explanation 

3. Which of the following statement is not correct about the  generation I of experiment of Meselson and stahl.
A. The E.Coli that was grown in ammonium chloride had 15N in its both strands of
DNA .
B. E. Coli was allowed to replicated in normal ammonium chloride in which 14N was present.
C. After replication, one strand of E.coli had DNA 14N and another strand had DNA 15N.
D. When E.coli was transferred in medium of ammonium chloride with 14N than E.coli had 14N in its both strands of DNA.
Answer: D Explanation

4. In generation I, E. Coli had been took time
A. 10 minutes 
B. 20 minutes
C. 40 minutes
D. 90 minutes
Answer: B Explanation

5. 15N could be differentiated from 14N on the basis of
A. Density B. Length
C. Volume D. No.of base pair
Answer: A Explanation

6. 15N could be differentiated from the 14N on the basis of A. Cesium chloride density gradient centrifugation.
B. Calcium chloride density gradient centrifugation.
C. Agarose gel electrophoresis
D. Pulse field gel electrophoresis
Answer: A Explanation

7. When E.coli was transferred in medium of ammonium chloride with 14N than E.coli had
A. 14N in its both strands of DNA.
B. 15N in its both strands of DNA.
C. 14N in its one strand and 15N in its another strands.
D. Both strands of DNA were devoid of Nitrogen.
Answer : C Explanation

8. Which of the following statement is correct about the  generation II of experiment of Meselson and stahl
A. Two molecules of DNA were produced and one  strand of both  DNA had 14N and another strand had 15N.
B.  Two molecules of DNA were produced and both  strand of both   DNA  molecule had 15N.
C. One molecules of DNA were produced and one  strand of  DNA molecule had 14N and another strand  had 15N.
D. One molecules of DNA were produced and both  strand of  DNA molecule had 14N.
Answer : C Explanation

9. Meselson and stahl observed second generation of E.coli after
A. 10 minutes 
B. 20 minutes
C. 40 minutes
D. 90 minutes
Answer: C Explanation
 
10. Which of the following option is correct about the  generation II  of experiment of Meselson and stahl in which two molecules of DNA were produced.
    First DNA     Second DNA
A.   15N                  15N
B.   14N                  14N
C.  14N & 15N        14N & 15N
D.  14N & 15N         15N
Answer: C Explanation

11. Given below are two statements and select the correct option
Statement I : Meselson and Stahl observed Hybrid DNA in both first and second generation.
Statement Il : One strand of Each DNA  had 14N and another strand had 15N.
A. Statement l is true and statement ll is false.
B. Statement l is false and statement ll is true.
C. Both statement I and II is true.
D. Both statement I and II is false.
 Answer: C Explanation

12. Given below are two statements and select the correct option
Statement I : Meselson and Stahl  proved that one strand is paternal (old) and another strand is newly synthesized.
Statement Il : One strand of Each  hybrid DNA  had 14N and another strand had 15N.
A. Statement l is true and statement ll is false.
B. Statement l is false and statement ll is true.
C. Both statement I and II is true.
D. Both statement I and II is false.
 Answer: C Explanation
   

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