NEET: Multiple Choice questions: Chromosomal Disorders

 

1.Which of the following is not associated with Aneuploidy.

A. There is loss of a  chromosome.

B. There is gain of complete set of chromosome.

C. There is gain of a chromosome.

D.It occur due to failure of segregation of  chromosome. 

Answer: B Explanation 

2.Which of the following is not associated with polyploidy.

A. There is loss or gain  of a  chromosome.

B. There is gain of complete set of chromosome.

C. It is often seen in plants.

D.It occur due to failure of cytokinesis during the telophase of  cell division .

Answer: B Explanation 

3. In trisomy or 2n + 1 :

A.  An additional copy of a chromosome may be included in an individual.

B. Individual may lack one of any one pair of chromosome.

C. A whole set of haploid set of chromosomes is added.

D. A whole set of haploid set of chromosomes is deleted.

Answer: A Explanation

4. In monosomy or 2n - 1 :

A.  An additional copy of a chromosome may be included in an individual.

B. Individual may lack one of any one pair of chromosome.

C. A whole set of haploid set of chromosomes is added.

D. A whole set of haploid set of chromosomes is deleted.

Answer: B Explanation

5.Which of the following chromosomal disorder is/are result trisomy.

A. Turner Syndrome

B.  Down Syndrome

C. Klinefelter Syndrome

D. Down syndrome and klinefelter syndrome.

Answer: D Explanation

6.Which of the following chromosomal disorder is/are result monosomy.

A. Turner Syndrome

B.  Down Syndrome

C. Klinefelter Syndrome

D. Down syndrome and               Klinefelter syndrome.

Answer: A Explanation

7.Down's Syndrome is caused  due to  the presence of an additional copy of the 

A. Chromosome number 21

B. Chromosome number 12

C. X Chromosome 

D. Y Chromosome 

Answer:A Explanation

8. Which of the following statement is / are correct about the Down syndrome.

A. It is caused by the trisomy of 21 chromosome 

B. This disorder was first described by Langdon Down in 1866. 

C.Down syndrome affected individual are Physical, psychomotor and mental development  retarded.

D. All of the above 

Answer: D Explanation

9. Consider the following symptoms of Down syndrome and select the correct code:

1. Short stature with small round head, 

2. furrowed tongue 

3. Partially open mouth 

4.Broad Palm with characteristic  crease

A. 1, 2 and 3

B. 2, 3 and 4

C. 1,3 and 4

D. 1, 2, 3 and 4

Answer: D Explanation

10. Klinefelter Syndrome is caused  due to  the presence of an additional copy of the 

A. Chromosome number 21

B. Chromosome number 12

C. X Chromosome 

D. Y Chromosome 

Answer:C Explanation

11. The karyotype of Klinefelter Syndrom is 

A. 22 + XYY

B. 22 + XXX

C. 22 + XXY

D. 22 + YYY

Answer: C Explanation

12. Which of the following statement is not correct about the klinefelter syndrome.

A. The individual with this genetic disorder has 47 chromosome.

B. The genetic constitution of this disorder is XXX and sex is female.

C. The individual with this disorder is sterile.

D. This is result of trisomy.

Answer: B Explanation

13.Gynaecomastia is one of the symptom of Klinefelter Syndrome. Gynaecomastia is

A. Development of ovary

B. Development of breast

C.Reduction of size of tested

D. Loss of skin pigmentation

Answer: B Explanation

 

14.Female with Rudimentary ovaries with lack of other secondary sexual characters is symptoms of 

A. Turner Syndrome

B.  Down Syndrome

C. Klinefelter Syndrome

D. All of the above

Answer: A Explanation

15. Given below are two statements and select the correct code:

Statement : I Turner syndrome is caused due to the absence of one of the X chromosomes. Statement : II Individual with Turner syndrome is    sterile female.

A. Both Statement I and statement Il is true.

B. Both Statement I and statement Il is false.

C. Statement I  is true and statement Il is false.

C. Statement I  is false and statement Il is true.

Answer: A Explanation

16. Which of the following statement is not correct about the Turner syndrome.

A. The individual with this genetic disorder has 45

chromosome.

B. The genetic constitution of this disorder is X0 and sex is female.

C. The individual with this disorder is sterile.

D. This is result of trisomy.

Answer: D Explanation