Stanley Miller and Urey proved experimentally the chemical theory of origin of life


  • It stated  that life gradually originated from inorganic molecules with the help of amino acids forming first and then they give rise to other biomolecules like proteins, glycoproteins, etc.
  • Stanley and Miller performed an experiment by creating the primitive conditions  in the laboratory. These  conditions were like the  atmosphere of the primitive earth. 

  • Under the guidance of his professor Harold Urey, Stanley Miller took Methane Ammonia and hydrogen in a 2:1:2 ratio in a two liter flask. Another flask that was filled with boiled water connected with the former flask.

  • This connection was to continue supply of water vapor through a glass tube.

  • As Oparin and Haldane demonstrate that the temperature of primitive earth was too high.

  • So He used two tungsten electrodes that were fitted to the larger flask to provide the temperature by the electric discharge.

  • That was created to bring the effect of lightning off the primitive atmosphere.


👌👌Remember This Miler apparatus was also called spark discharge apparatus

  • The larger flask was connected to a small U shaped tube by means of a straight tube passing through a condenser.

  • The water in the second  flask was heated and the released water vapor was added to the chemical mixture.

  • When the electrodes were used to spark the temperature that was similar to the  lightning and storm of primitive earth.

  • The water vapors were cooled and the water condensed. This condensed water trickles back in the first water flask in a continuous cycle.

  • This experiment continued  for about a week. After a week Miller and Urey observed that a dark color liquid was condensed in a U shaped  tube.

  • This liquid was a mixture of simple amino acids like glycine alanine and organic acids.

  • By this it was proved that first life on earth was like a proteinaceous structure that was originated according to the oparin and Haldane hypothesis.





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